Studies

I have worked with some of the leading PPS authorities in France including Helena Kopecka and Isabelle LeParc at the Pasteur Institute, Jacque Julien at the University of Bordeaux and Bruno Lina and Michelle Ayrnard at the WHO reference lab in Lyon. We have found enteroviral RNA in the cerebrospinal fluid of a majority of patients with PPS by polymerase chain reaction. I have subsequently completely sequenced the virus, and found it to be a defective interfering virus with 83.3% homology with Sabin type 2 poliovinis. We have also found immune suppression in these patients. A very effective treatment is immune globulin in combination with ENERCEL^®